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Best Diaper Rash Creams of 2026, by Rash Type

Updated
One tube rarely fixes every rash. Here is how to match cream to bottom.

Our Top Picks

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Image
Model
Product Comparison Table
Features

Product Image of the The Honest Company Diaper Rash Cream, Hypoallergenic, Cruelty-Free, 2.5 oz
Best Organic Diaper Rash Cream
The Honest Company
  • Plant-based
  • NSF certified
  • Hypoallergenic
Product Image of the Aquaphor Baby Diaper Rash Cream with Zinc Oxide, Multipack, 3 x 3.5 OZ
Best Diaper Cream for Infants
Aquaphor Baby 3-in-1
  • 15% zinc oxide
  • Fragrance-free
  • Gentle for infants
Product Image of the Triple Paste Diaper Rash Cream, Zinc Oxide Baby Ointment, 3 oz
Best Diaper Rash Cream for Sensitive Skin
Triple Paste
  • 12.8% zinc oxide
  • Hypoallergenic
  • Oat extract & beeswax
Product Image of the Desitin Maximum Strength Diaper Rash Paste, 40% Zinc Oxide, 4.8 oz
Best Maximum Strength Diaper Rash Cream
Desitin Maximum Strength
  • 40% zinc oxide
  • Up to 12-hour protection
  • Dermatologist tested
Product Image of the Boudreaux’s Butt Paste Maximum Strength Diaper Rash Cream, 4 Oz
Best Diaper Cream for Toddlers
Boudreaux’s Butt Paste
  • Fast-acting
  • Simple formula
  • Pharmacist developed
Product Image of the Weleda Baby Calendula Diaper Cream, 2.8 Fluid Ounce, Plant Rich Protection with Calendula, Chamomile, Sweet Almond Oil, Lanolin and Zinc Oxide
Best Diaper Rash Cream for Open Sores
Weleda Diaper Cream
  • Calendula extract
  • Breathable barrier
  • No synthetic preservatives
Product Image of the A+D Overnight Healing Diaper Rash Ointment, with Vitamins, Lavender, 3.6 Oz
Best Diaper Cream for Eczema
A&D Overnight Healing
  • Vitamins A & D
  • Colloidal oatmeal
  • Overnight healing
Product Image of the Aquaphor Baby Advanced Therapy Healing Ointment Skin Protectant, 14 OZ
Best Diaper Rash Cream for Diarrhea
Aquaphor Baby Healing Ointment
  • Petrolatum barrier
  • Wipes off easily
  • Multi-use
Product Image of the Baza Antifungal Skin Protectant 5 oz. Tube Scented 1607, 1Ct
Best Antifungal Diaper Rash Cream
Baza Moisture Barrier
  • Miconazole antifungal
  • Moisture barrier
  • For yeast rashes

Our Review Criteria: The active skin protectant and its concentration decide a diaper rash cream: zinc oxide runs from about 10 to 40 percent, petrolatum seals differently, and an antifungal treats a different rash entirely. We ranked each formula on that active, on how well it seals out moisture, on how gently it wipes off already-raw skin, and on how short the ingredient list stays for sensitive babies. We weighed those judgments against pediatric and dermatology guidance from the Mayo Clinic, the American Academy of Pediatrics, and Consumer Reports, and we note when a rash needs a doctor rather than a cream. We verify every pick is still sold and swap out any discontinued product.

When your baby is hurting, you want relief now. A good diaper rash cream goes to work the moment it touches a raw, red bottom, sealing out the wetness that keeps the skin irritated.

As moms, we know one tube does not fix every rash. A mild redness, a yeast flare, and an eczema-prone bottom each need a different formula, so we sorted the options by the job they actually do.

Below are our picks for the best diaper rash creams, matched to the kind of rash you are fighting, with the ingredients and guidance to back each one up.


Why You Need Diaper Rash Cream

A diaper rash is simply a skin irritation in your child’s diaper area, but it can cause major distress.

Sometimes it appears as a small, red patch that doesn’t seem to bother your baby. Other times, it can be severe, spreading to the thighs or tummy and causing genuine pain. in extreme cases, the skin can even bleed or become infected.

Diaper rash cream helps heal your child’s bottom from an existing rash and prevents new ones from flaring up.

The best creams act as a protective barrier between your baby’s sensitive skin and potential irritants like urine or poop. They also include soothing ingredients to calm inflammation and speed up recovery.

The Causes of Diaper Rash

While sensitive skin is a factor, there are several specific culprits behind diaper rash:

  • Moisture: Diapers are warm, humid environments. Even the best diapers can’t keep a bottom 100 percent dry, and trapped moisture eventually breaks down the skin (1).
  • Stool: When urine mixes with stool, it creates ammonia. This chemical is harsh and burns the skin. If you are a cloth diaper user, you must keep cloth diapers free of ammonia buildup.
  • Diarrhea: Loose stools are more acidic than regular bowel movements. The combination of acid, moisture, and frequent wiping creates a perfect storm for severe rashes.
  • Foods: New foods change the chemical composition of your baby’s stool. Acidic foods (like tomatoes or strawberries) can lead to irritating poop. Note that this doesn’t always mean an allergy, just a sensitivity to the acid.
  • Chemicals: Disposable diapers contain dyes, gels, and perfumes. If your child gets frequent rashes, consider switching to a dye-free diaper for sensitive skin or trying cloth diapers.
  • Detergents: If you use cloth diapers, your baby might react to your laundry detergent. Try an extra rinse cycle or switch to a free-and-clear brand.
  • Antibiotics: Medicine kills bad bacteria, but it also wipes out the “good” bacteria that keeps yeast in check. This often leads to yeast infections or diarrhea, both of which cause rashes.
  • Yeast: Yeast (technically a fungus) thrives in warm, moist places. Unlike a standard rash, a yeast infection usually requires an antifungal treatment and won’t go away with standard cream alone (2).

Pro Tip

If you use cloth diapers and your child develops a yeast rash, you must sanitize your diapers. Regular washing won’t kill the yeast living in the fibers. Switch to disposables temporarily and treat your cloth stash to prevent reinfection.

Types of Diaper Rash Products

Different rashes require different treatments, so here is a breakdown of what is available:

Creams

Creams are water-based formulations. They spread easily, absorb quickly, and are generally best for soothing mild irritation rather than treating severe, open sores.

Pastes

Pastes are thick, heavy, and often contain a high percentage of zinc oxide. They are excellent for protecting the skin and treating moderate to severe rashes. Note that they can stain clothing and are difficult to wash out of cloth diapers without a liner.

Ointments

Ointments are oil-based (often petroleum). Because they are greasy, they sit on top of the skin to create a waterproof seal. This is ideal for preventing rashes or protecting the skin during bouts of diarrhea.

Powders

Powders absorb moisture, but most pediatricians now recommend against them. The fine particles can become airborne and damage your baby’s lungs if inhaled. If you must use powder, place it in your hand away from the baby first, and never use talc-based products.

How to Choose a Diaper Rash Cream

Before buying a tube, consider these factors to find the right match for your baby:

Type of Rash

If the bottom is just red, a traditional zinc-oxide cream or petroleum ointment works well. If the rash has defined borders, red dots (satellite lesions), and won’t go away, it might be yeast. In that case, you need an antifungal product.

Cream, Paste, or Ointment

Use ointments for prevention (daily use). Use creams for mild irritation. Use thick pastes (usually 40% zinc oxide) for severe rashes that need a heavy-duty barrier to heal.

Cloth or Disposable Diapers

If you use disposable diapers, you can use any cream you like. If you use cloth, petroleum and zinc oxide can clog the fabric fibers, causing leaks. Look for “cloth safe” creams or use a disposable liner.

Ingredients

Some babies have ultra-sensitive skin that reacts to the cream itself. Check labels for potential allergens like lanolin (sheep’s wool oil), beeswax, mineral oil, or essential oils if your baby has a history of skin reactions.


Product Reviews

We compared the formulas, checked the active ingredients, and matched each pick to the type of rash it handles best.

The Honest Company Diaper Rash Cream

Best Organic Diaper Rash Cream

Our Rating4.25 / 5
Ingredients
4.5 / 5
Effectiveness
4.5 / 5
Hypoallergenic
4.5 / 5
Consistency
3.5 / 5
Total Rating
4.25 / 5

The Honest Company diaper rash cream is the pick for parents who want plant-based ingredients without giving up a real zinc barrier. It leans on zinc oxide for protection alongside organic shea butter and jojoba esters to help heal the skin.

It carries an NSF certification for its organic content and leaves out synthetic fragrance, dyes, silicones, and petrolatum. The texture spreads easily but still sets up as a barrier, a middle ground between a light lotion and a heavy paste.

Because it uses natural oils, the cream can separate and may need a stir, and the coconut-derived ingredients could bother a baby with a specific sensitivity. For most families wanting a cleaner label, it delivers.

Pros

  • NSF-certified organic content.
  • Plant-based, with no synthetic fragrance, dyes, or petrolatum.
  • Spreadable texture that still forms a barrier.

Cons

  • Natural oils can separate and need stirring.
  • Coconut-derived ingredients may bother some sensitivities.
  • Costs more than drugstore zinc creams.

Product Specs

Type Zinc oxide cream
Active Ingredient Zinc oxide
Size 2.5 oz tube
Key Ingredients Zinc oxide, shea butter, jojoba esters
Free Of Synthetic fragrance, dyes, silicones, petrolatum
Best For Plant-based, organic-minded parents

Aquaphor Baby 3-in-1 Diaper Rash Cream

Best Diaper Cream for Infants

Our Rating4 / 5
Ingredients
4 / 5
Effectiveness
4 / 5
Hypoallergenic
4.5 / 5
Consistency
4 / 5
Total Rating
4 / 5

For a newborn’s delicate skin, a gentle everyday cream usually beats a heavy medicated paste, and Aquaphor Baby 3-in-1 fits that role. It is designed for mild to moderate rash and for the first signs of irritation, exactly the stage most infant rashes are caught.

It pairs 15% zinc oxide with panthenol (3), so it treats and soothes while sealing out wetness, but it stays light enough to spread easily on tiny skin. The formula is free of fragrance, parabens, preservatives, and dyes, which trims the list of things a sensitive infant can react to.

As a lighter cream it is not the pick for a severe, weeping rash, where a 40% zinc paste wins. It also comes as a multi-pack, which is convenient but more than a first-time parent may want to commit to.

Pros

  • 15% zinc oxide plus panthenol treats and protects.
  • Free of fragrance, parabens, preservatives, and dyes.
  • Light texture spreads easily on newborn skin.

Cons

  • Too light for a severe, weeping rash.
  • Sold as a multi-pack.
  • Zinc and petrolatum are not ideal for cloth diapers.

Product Specs

Type Zinc oxide cream
Active Ingredient Zinc oxide 15%, panthenol
Size 3.5 oz tube
Free Of Fragrance, parabens, preservatives, dyes
Best For Infants and mild to moderate rash

Triple Paste Diaper Rash Cream

Best Diaper Rash Cream for Sensitive Skin

Our Rating4 / 5
Ingredients
4 / 5
Effectiveness
4.5 / 5
Hypoallergenic
4.5 / 5
Consistency
3.5 / 5
Total Rating
4 / 5

Triple Paste is the pick when a baby reacts to everything else. It is a pediatrician-recommended, hypoallergenic ointment built around a short list of skin-friendly ingredients, which is why sensitive-skin parents keep coming back to it.

The active ingredient is 12.8% zinc oxide, backed by oat extract, beeswax, and glycerin to calm and condition irritated skin. It leaves out fragrance, parabens, preservatives, talc, phthalates, and dyes, so there is little in the tube to trigger a reaction.

The paste is thick and can feel heavy going on, and it is pricier than drugstore staples. But for stubborn or recurring irritation on reactive skin, that dense barrier is the reason it works.

Pros

  • Hypoallergenic, with a short ingredient list for reactive skin.
  • 12.8% zinc oxide with soothing oat extract and beeswax.
  • Free of fragrance, parabens, preservatives, talc, and dyes.

Cons

  • Thick paste feels heavy to apply.
  • Costs more per ounce than drugstore brands.
  • Zinc-and-beeswax base can clog cloth fibers.

Product Specs

Type Zinc oxide ointment
Active Ingredient Zinc oxide 12.8%
Size 3 oz tube
Key Ingredients Zinc oxide, oat extract, beeswax, glycerin
Free Of Fragrance, parabens, preservatives, talc, phthalates, dyes
Best For Sensitive, reaction-prone skin

Desitin Maximum Strength Zinc Oxide Diaper Rash Paste

Best Maximum Strength Diaper Rash Cream

Our Rating3.75 / 5
Ingredients
3.5 / 5
Effectiveness
5 / 5
Hypoallergenic
4.5 / 5
Consistency
2.5 / 5
Total Rating
3.75 / 5

Desitin Maximum Strength is the tube parents reach for when a rash looks raw and painful. This is the paste version, packing 40% zinc oxide (4), the maximum strength you can buy over the counter.

That heavy zinc load is the whole point. It lays down a thick, opaque barrier that seals wetness away from the skin and holds for up to 12 hours, so a bedtime layer is still working by morning. It is hypoallergenic and skips parabens and dyes.

The tradeoff is texture. This paste is stiff and sticky, so it clings to your fingers and takes effort to wipe off, and the zinc smell is noticeable. For a mild pink bottom it is overkill, but for a serious flare it is hard to beat.

Pros

  • 40% zinc oxide, the maximum over-the-counter strength.
  • Seals out wetness for up to 12 hours.
  • Hypoallergenic, with no added parabens or dyes.

Cons

  • Thick, sticky paste is hard to wipe off skin and hands.
  • Distinct zinc scent.
  • Too heavy for everyday mild redness.

Product Specs

Type Zinc oxide paste
Active Ingredient Zinc oxide 40%
Size 4.8 oz tube
Free Of Parabens, dyes
Protection Up to 12 hours
Best For Severe, stubborn rashes overnight

Boudreaux’s Butt Paste Diaper Rash Ointment

Best Diaper Cream for Toddlers

Our Rating3.75 / 5
Ingredients
3.5 / 5
Effectiveness
4.5 / 5
Hypoallergenic
3.5 / 5
Consistency
3.5 / 5
Total Rating
3.75 / 5

Boudreaux’s Butt Paste was developed by a pharmacist and father, and it keeps the formula short on purpose. For a toddler who fights every diaper change, that simple, fast-working approach is a real advantage.

Zinc oxide does the heavy lifting, laying down a visible layer that blocks wetness and gives irritated skin room to recover. Peruvian balsam adds a mild soothing note, and the scent is pleasant rather than medicinal.

Parents often see redness fade within a change or two. Like any zinc-and-petrolatum paste it can clog cloth diaper fibers, so pair it with a liner if you use cloth.

Pros

  • Short, pharmacist-designed ingredient list.
  • Thick zinc layer covers well and works fast.
  • Mild, non-medicinal scent toddlers tolerate.

Cons

  • Not cloth-diaper friendly without a liner.
  • Contains petrolatum.
  • Thicker paste can be pricier per ounce.

Product Specs

Type Zinc oxide ointment
Active Ingredient Zinc oxide
Size 4 oz tube
Key Ingredients Zinc oxide, Peruvian balsam
Best For Toddlers and fast visible relief

Weleda Diaper Cream with Calendula

Best Diaper Rash Cream for Open Sores

Our Rating3.75 / 5
Ingredients
4 / 5
Effectiveness
4.5 / 5
Hypoallergenic
3 / 5
Consistency
4 / 5
Total Rating
3.75 / 5

Developed with midwives, Weleda’s calendula diaper cream is a long-standing favorite in Europe and the US for angry, inflamed skin. Its focus is the anti-inflammatory calendula (marigold) extract rather than a heavy occlusive block.

It uses a lower 12% zinc oxide, which rubs in more easily while still offering protection, and the beeswax leaves a breathable layer while sweet almond oil keeps skin soft. That makes it gentle enough to work around tender, broken skin.

The herbal scent is strong and it does contain lanolin and sesame oil, so check labels if your baby has those allergies. For raw, red skin that needs calming more than a thick seal, it is a thoughtful choice.

Pros

  • Anti-inflammatory calendula extract calms red skin.
  • Lower 12% zinc rubs in without a heavy block.
  • No synthetic preservatives or fragrances.

Cons

  • Strong herbal scent.
  • Contains lanolin and sesame oil, common allergens.
  • Breathable layer is less protective against heavy wetness.

Product Specs

Type Zinc oxide cream
Active Ingredient Zinc oxide 12%
Size 2.8 oz tube
Key Ingredients Zinc oxide, calendula extract, beeswax, sweet almond oil, lanolin
Free Of Synthetic preservatives, fragrances
Best For Red, inflamed skin and open-sore care

A&D Overnight Healing Diaper Rash Ointment

Best Diaper Cream for Eczema

Our Rating3.75 / 5
Ingredients
3.5 / 5
Effectiveness
4.5 / 5
Hypoallergenic
3 / 5
Consistency
4 / 5
Total Rating
3.75 / 5

Eczema-prone skin needs soothing as much as sealing, and A&D Overnight Healing is formulated for that overnight repair window. It combines Vitamins A and D with colloidal oatmeal, a classic ingredient for calming itchy, irritated skin.

The ointment goes on smooth and clear, so it does not stain, and it works to relieve redness, dryness, and itching while your baby sleeps. It skips parabens, dyes, and phthalates, which suits reactive skin.

It does carry a light lavender scent, so a truly fragrance-free household should look elsewhere. But for a bottom that is both rashy and eczema-flared, the oatmeal-and-vitamin approach targets the inflammation, not just the wetness.

Pros

  • Colloidal oatmeal and Vitamins A and D calm irritated skin.
  • Clear ointment that does not stain.
  • Free of parabens, dyes, and phthalates.

Cons

  • Light lavender scent is not for fragrance-free households.
  • Ointment feel is greasier than a cream.
  • A pure barrier paste protects better against heavy wetness.

Product Specs

Type Healing ointment
Active Ingredient Skin protectant with Vitamins A and D
Size 3.6 oz tube
Key Ingredients Vitamins A and D, colloidal oatmeal, lavender
Free Of Parabens, dyes, phthalates
Best For Eczema-prone, itchy skin overnight

Aquaphor Baby Healing Ointment for Diaper Rash

Best Diaper Rash Cream for Diarrhea

Our Rating3.25 / 5
Ingredients
3 / 5
Effectiveness
4.5 / 5
Hypoallergenic
3 / 5
Consistency
3 / 5
Total Rating
3.25 / 5

When diarrhea is the culprit, the job changes from healing to shielding, and Aquaphor Baby Healing Ointment is built for that. This clear, petrolatum-based ointment spreads on smooth and wipes off without scrubbing, which matters when a bottom is raw from frequent loose-stool changes.

It has no zinc oxide. Instead the petrolatum forms a waterproof seal, and panthenol and glycerin help condition the skin underneath. Think of it as a barrier against acidic stool rather than a medicated rash treatment.

The same ointment doubles for drool rash, chapped cheeks, and minor scrapes, so the big jar earns its shelf space. It does feel greasy, and because it is a protectant rather than a zinc treatment, a severe established rash may need something stronger.

Pros

  • Wipes off easily on raw, sensitive skin.
  • Petrolatum seal protects against acidic, loose stool.
  • Multi-use for drool rash, dry cheeks, and scrapes.

Cons

  • Greasy feel on hands.
  • No zinc oxide, so less of a treatment for severe rashes.
  • Petrolatum base is not cloth-diaper friendly.

Product Specs

Type Petrolatum ointment
Active Ingredient Petrolatum (skin protectant)
Size 14 oz jar
Key Ingredients Petrolatum, panthenol, glycerin
Free Of Fragrance, preservatives
Best For Diarrhea and an everyday moisture barrier

Baza Moisture Barrier Antifungal Cream

Best Antifungal Diaper Rash Cream

Our Rating3.25 / 5
Ingredients
3 / 5
Effectiveness
4 / 5
Hypoallergenic
2.5 / 5
Consistency
4 / 5
Total Rating
3.25 / 5

A standard barrier cream will not clear a yeast rash, and that is exactly the gap Baza fills. It is a moisture-barrier cream used in professional nursing care that many parents turn to for stubborn fungal rashes.

The active ingredient is miconazole nitrate, an antifungal, combined with a protectant base. That two-part action kills the yeast while shielding the skin from further moisture damage, which a plain zinc cream cannot do.

Because it is a medicated antifungal, it belongs in the doctor-approval category. Talk to your pediatrician before using it on a baby, and if a suspected yeast rash does not improve in a couple of days, get it looked at.

Pros

  • Contains miconazole nitrate to treat yeast.
  • Pairs the antifungal with a moisture barrier.
  • Clears stubborn fungal rashes a plain cream cannot.

Cons

  • Contains added fragrance and synthetic ingredients.
  • Needs pediatrician approval for infant use.
  • Not for routine, non-fungal rashes.

Product Specs

Type Antifungal barrier cream
Active Ingredient Miconazole nitrate
Size 5 oz tube
Best For Yeast (candidal) rashes with pediatrician approval
Note Medicated; doctor approval advised

Product Comparison Chart

Product Best For Type Standout
The Honest Company Best Organic Cream Plant-based, NSF certified
Aquaphor Baby 3-in-1 Best for Infants Cream 15% zinc, fragrance-free
Triple Paste Best for Sensitive Skin Ointment Hypoallergenic, no fragrance
Desitin Maximum Strength Best Maximum Strength Paste 40% zinc oxide
Boudreaux’s Butt Paste Best for Toddlers Ointment Fast visible relief
Weleda Diaper Cream Best for Open Sores Cream Calendula, breathable
A&D Overnight Healing Best for Eczema Ointment Vitamins A and D, oatmeal
Aquaphor Baby Healing Ointment Best for Diarrhea Ointment Wipes off raw skin easily
Baza Moisture Barrier Best Antifungal Cream Miconazole antifungal

FAQs

Is Diaper Rash Fungal or Bacterial?

Diaper rash can be either, and the type decides the treatment. Most cases are simple contact dermatitis from moisture and friction. A yeast (fungal) rash looks beefy red with small satellite spots and needs an antifungal, while oozing, crusting, or open sores can signal a bacterial infection that a doctor should see.

Can Diaper Cream Make a Rash Worse?

Yes, diaper cream can occasionally make a rash worse if you seal an unclean area. Trapping yeast or bacteria under a thick layer of paste or petroleum jelly on skin that was not cleaned and dried first gives the infection a warm place to grow. Always apply cream to clean, dry skin.

Is Diaper Rash Cream Ok for Adults?

Diaper rash cream is safe for adults. Adult skin is tougher than a baby’s, so any zinc oxide or petrolatum product gentle enough for an infant works fine for adult chafing, incontinence irritation, or friction rashes.

Is It Ok to Use Diaper Cream at Every Change?

Using diaper cream at every change is fine and is smart prevention with a petrolatum or low-zinc ointment. A thin barrier at each change keeps urine and stool off the skin. With a heavy medicated zinc paste, you usually only need it when redness appears.

What Diaper Cream Do Dermatologists Recommend?

Dermatologists generally recommend a high zinc oxide cream like Desitin for treating an active rash, and a simple petrolatum ointment like Aquaphor for daily prevention on sensitive skin. Both use well-studied skin protectants with few added ingredients, which Consumer Reports also favors.

What Is the Best Cream for a Diaper Rash?

The best cream for a diaper rash depends on its severity. For a severe, raw rash, Desitin Maximum Strength with 40% zinc oxide builds the heaviest barrier. For daily prevention or mild redness, a lighter option like Aquaphor keeps skin protected without a thick paste.

How Much Diaper Cream Should I Apply?

Apply diaper cream generously, coating the whole diaper area in a visible layer. The goal is a barrier thick enough that the next time your baby pees or poops, the mess meets the cream instead of the skin. You do not need to rub it all the way in.

How Long Does Diaper Rash Take to Heal?

Most diaper rashes clear within two to three days once you keep the area clean and dry and use a zinc oxide barrier cream at every change. If the rash has not improved after about three days, looks like a yeast infection, or has open sores, call your pediatrician.

The Bottom Line

Our top pick is Desitin Maximum Strength Zinc Oxide Diaper Rash Paste. Its 40% zinc oxide lays down the thickest barrier on this list, so an angry overnight rash has a real chance to heal by morning.

The right cream usually takes a little trial and error. Once you find the one that clears your baby’s skin, stock up: keep a tube at the changing table, one in the diaper bag, and maybe one at grandma’s house too.

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Headshot of Mary Sweeney, BSN, RN, CEN

Reviewed by

Mary Sweeney, BSN, RN, CEN

Mary Sweeney, BSN, RN, CEN is an oncology nurse navigator and freelance medical writer. Mary has 4 years of experience as an officer in the Navy Nurse Corps. including emergency/trauma, post-anesthesia, and deployment medicine.